Investor Presentaiton

Investor presentation Full year 2018 The GLP-1 segment accounts for 14% of the global diabetes care market value Slide 69 Global GLP-1 market GLP-1 value in bDKK VictozaⓇ Exenatide OzempicⓇ Other Dulaglutide Share of total diabetes care market Share of total diabetes care GLP-1 value and patient share of the total diabetes care market GLP-1 value share of total diabetes GLP-1 patient share¹ of total diabetes market 80 10% 20% 17% 70 - 8% 60 CAGR value¹: 35.4% 14% 15% 12% 50 6% 40 10% 4% 30 7% 6% 6% 5% 20 5% 3% 2% 10 1% 0 Nov 2013 0% 0% Nov 2018 World North Reg Reg America EU LATAM Reg J&K Reg Reg AAMEO China 1 CAGR for 5-year period Source: IQVIA monthly MAT Nov, 2018 value figures changing diabetes Reg: Region; AAMEO: Africa, Asia, the Middle-East and Oceania; J&K: Japan & Korea; LATAM: Latin America 1 Patient share is indicative and based on data for the USA, the UK, Germany and France only. Source: Value data; IQVIA monthly MAT Nov, 2018. Patient data; IQVIA Disease Analyser (DE, FR, UK), Quintiles IQVIA LRX (USA), Nov 2018

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