Q4 2021 Results slide image

Q4 2021 Results

Participants Company overview Pharmaceuticals Oncology Financial review Conclusion Appendix Financial performance Innovation: Pipeline overview Innovation: Clinical trials CRM IHD Neuroscience Ophthalmology Respiratory & Allergy Oncology: Solid Tumors Hematology Biosimilars Global Health Abbreviations canakinumab - IL-1 beta inhibitor Study Indication Phase Patients Primary Outcome Measures Arms Intervention Target Patients NCT03447769 CANOPY-A (CACZ885T2301) Adjuvant NSCLC Phase 3 1500 Disease free survival (primary), overall survival (key secondary) Canakinumab 200mg q3w sc for 18 cycles Placebo q3w sc for 18 cycles Patients with: High-risk NSCLC (AJCC/UICC v.8 stage II-IIIA and IIIB (T>5cm N2)) after complete resection and standard of care adjuvant cisplatin-based chemotherapy All histologies Read-out Milestone(s) 2022 Publication TBD 116 Investor Relations | Q4 2021 Results NOVARTIS | Reimagining Medicine
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