EVOLUTION AT MERCK - INVENTING FOR LIFE

30 YEARS OF HIV INNOVATION CONTINUES 1980s 1983 HIV is discovered 1990s 2000s 1996 CRIXIVAN (dinovir sulfate, MSD) 1989 Role of protease published - AZT launches 1998 Once Daily STOCRIN (efavirenz) 1African Comprehensive HIV/AIDS Partnerships 2010s 2020+ 2000 ACHAP1 Partnership with Botswana and Bill and Melinda Gates Foundation 2007 2017 Isentress HD raltegravir 2018 Pifeltro doravirine aleta 000 ** CONTINUING TO INNOVATE MK-8591: Investigational NRTTI for the treatment and prevention of HIV Many additional mechanisms in early development ISENTRESS raltegravir film-coated tablets 400 mg Delstrigo doravirine/lamivudine/ tenofovir disoproxil fumarate MERCK Dr. Roy Baynes | INVENTING FOR LIFE 67 20

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