RSV Seasonal Vaccine Introduction and Growth Strategy slide image

RSV Seasonal Vaccine Introduction and Growth Strategy

68 potential new vaccines and medicines in pipeline Phase III / Registration – 17 assets Arexvy (RSV vaccine) gepotidacin (2140944) bepirovirsen (3228836) Bexsero (MenB vaccine) MenABCWY vaccine (3536819) tebipenem pivoxil (3778712) ibrexafungerp (5458448) Nucala (mepolizumab) depemokimab (3511294) latozinemab (4527223) camlipixant (5464714) momelotinib (3070785) Jemperli (dostarlimab) Zejula (niraparib) Blenrep (belantamab mafodotin) cobolimab (4069889) linerixibat (2330672) Recombinant protein, adjuvanted* BTI inhibitor* Antisense oligonucleotide* Recombinant protein, OMV Recombinant protein, OMV, conjugated vaccine Antibacterial carbapenem* Antifungal glucan synthase inhibitor* Anti-IL5 antibody Long-acting anti-IL5 antibody* Anti-sortilin antibody* P2X2/P2X3 receptor antagonist* JAK1, JAK2 and ACVR1 inhibitor* Anti-PD-1 antibody* PARP inhibitor* Anti-BCMA ADC* Anti-TIM-3 antibody* IBAT inhibitor RSV older adults^8 Uncomplicated UTI** Hepatitis B virus** Meningitis B (infants US) MenABCWY, 1st Gen Complicated UTI⁹ Invasive candidiasis COPD Asthma** Frontotemporal dementia 10** Refractory chronic cough Myelofibrosis^ Endometrial cancer^** Ovarian cancer** Multiple myeloma Non-small cell lung cancer Cholestatic pruritus in primary biliary cholangitis Infectious diseases HIV (VIIV) Respiratory/Immunology Oncology Opportunity driven GSK *In-license or other alliance relationship with third party ** Additional indications or candidates also under investigation In registration 1. In phase I/II study 2. Transition activities underway to enable further progression by partner 3. GSK has an exclusive global license option to co-develop and commercialise the candidate 4. Imminent study start 5. GSK has exclusive option to co-develop post phase II 6. Phase II/III study start expected in 2023 7. Phase II study start expected in 2023 8. Approved in US and EU 9. Phase III study start expected in 2023 10. Phase III trial in patients with progranulin gene mutation 39
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