Investor Presentaiton

Clinical use case: Silicosis 1 2 Validated assessment of regional lung function Reliable repeatability of findings TV: Tidal Volume VH: Ventilation Heterogeneity VDP: Ventilation Defect Percentage HEALTHY DISEASE Healthy Male, Mid - 30s INITIAL SCAN D TV VH VDP 0.68 42.8 13.0 FOLLOW-UP SCAN (3 months later) 4DMedical Limited (ASX:4DX) Investor Presentation | September 2022 36-year-old man with Severe, Progressive Silicosis INITIAL SCAN TV VH 0.50 54.5 VDP 17.3 FOLLOW-UP SCAN (3 months post-treatment) 3 4 TV VH VDP TV VH VDP 0.59 47.3 13.8 0.77 44.5 13.8 4DMedical™ Quantification of regional ventilation defects Effective monitoring of disease and treatment effects 15

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