AstraZeneca Results Presentation Deck slide image

AstraZeneca Results Presentation Deck

BioPharmaceuticals: Respiratory and Immunology Total Revenue $6.0bn; growth +9% $m 400 300 200 100 ● 0 ● Q4 2019 Fasenra 31% growth to $1.3bn Q1 Q2 Q3 Q4 Q1 US Europe EROW EM 2020 Q2 Q3 Q4 Leading biologic in eosinophilic asthma¹ • Global performance driven by new patient share Now a blockbuster medicine 2021 Fasen 730 mg/ml Breztri COPD launch progressing; sales of $203m T8 triple FDCs brand share (DOT)² 4% 13% Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Global launch underway with 13% triple FDC branded market share in T8 countries, with 23% share in US, CN, JP Demand sales volume increase in China following NRDL inclusion Saphnelo SLE launch progressing • Positive early market response, despite COVID-19 headwinds US: $8m sales, with 35% NBRx share of i.v. market³ Japan: formulary listing submissions are proceeding EU CHMP positive opinion 23 1. Based on IQVIA MIDAS consolidated total patient top-7 market share (markets: US, JP, DE, FR, ES, IT, UK) in Q3 2021. 2. IQVIA MIDAS monthly days of therapy month end November 2021. 3. IQVIA LAAD claims data. NBRX = new to brand prescriptions; COPD = chronic obstructive pulmonary disorder; FDC = fixed dose combinations; i.v. = intravenous. NDC 0310-3040-00 Saphnelo (anifrolumab-fnia) Injection Rx only 300 mg/2 mL (150 mg/mL) For Intravenous Infusion After Dilution Must dilute before use. See prescribing information. Single-dose vial Discard unused portion Store refrigerated at 2°C to 8°C (36°F to 46°F). Ceep vial in original carton to protect from light. Jo not shake or freeze. aphnel tion 300 single-dose vial Ma only AstraZeneca 4
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