Investor Presentaiton

High adherence and patient preference. drives ~40% increased S&M productivity INVESTOR 20 DAY 23 [] cologuard shield™ Orders Placed 100 100 Adherence Orders Resulted 65%¹ 90%2 65 90 GUARDANT™ 1. 4. EXACT Sciences presentation at Goldman Sachs 44th Annual Global Healthcare Conference, June 2023 2. Guardant data on file 120

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