Investor Presentaiton

sanofi Acne is chronic inflammatory skin disease and the 8th most common medical condition globally Mild acne 12/12/2001 Moderate acne Severe acne High burden of disease - Chronic nature of condition - Psycho-social impact on patients Contribution to antimicrobial resistance Economic impact of treatment Unmet needs with current treatments Incidence and prevalence significant and increasing - 8.6 million prevalent cases in U.S. 18.3 million prevalent cases in EU Source: IHME/GBD 2019 estimates. Available at https://vizhub.healthdata.org/qbd-compare/ Chen H. et al. Magnitude and temporal trend of acne vulgaris burden in 204 countries and territories from 1990 to 2019: an analysis from the Global Burden of Disease Study 2019 Layton A. M. et al. Reviewing the global burden of acne: how could we improve care to reduce the burden? 105 Vaccines Investor Event

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