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Investor Presentaiton

Serplulimab Entered into a New High-growth Stage of Commercialization with Differentiated Advantage 6 MI J 1.12B RMB • 2023 sales revenue reached 1.12B RMB In March 2023, Serplulimab achieved over RMB 100M monthly sales in China for the first time, representing its commercialization stepping up into new stage By the end of 2023, Serplulimab has completed tendering platform listing for all 31 provinces in China, and established a commercial team of ~580 people with strong professional communication skills and sales experience in oncology Clinical Advantages Serplulimab recommended by 9 Diagnosis and Treatment Guidelines of CSCO in 2023 Including 2023 CSCO Diagnosis and Treatment Guidelines for SCLC, NSCLC, EC, CRC and Clinical Application Guideline for immune checkpoint Inhibitor etc. ASTRUM-004 • • In 2023 WCLC, oral presentation of the final analysis results of total population for the first time In 2023 ESMO Asia, the data from the Asian subgroup were showcased in a poster session In 2024, published online in Cancer Cell as its cover feature Differentiated Indications ES-SCLC (marketed): ASTRUM-005 mOS: 15.8 vs 11.1 months GC (Phase III): Expected to be the world leading and the only perioperative immune drug in China for GC LS-SCLC (Phase III): Expected to be the world's first PD-1 for the treatment of LS-SCLC mCRC (Phase II/III): Phase II clinical data of 1L mCRC has been presented in ASCO GI with the mPFS of 17.2 months; expected to become the first approved PD-(L)1 for 1L mCRC O 2024 Henlius. 2 Henlius
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