Investor Presentation - First Six Months of 2021 slide image

Investor Presentation - First Six Months of 2021

63 Investor presentation First six months of 2021 Novo NordiskⓇ In STEP 8, semaglutide 2.4 mg showed weight loss of 17.1% compared to 6.6% with liraglutide 3.0 mg 0 STEP 8 observed mean change in body weight¹ Mean baseline body weight: 104.5 kg Statistically significant weight loss with sema 2.4 mg vs lira 3.0 mg Mean baseline body weight: 104.5 kg 0 % change in body weight S -10 -15 -20 05 Sema 2.4 mg Lira 3.0 mg Placebo 10 15 20 25 30 35 40 45 50 55 60 65 68 % change in body weight -5 -10 -6.6 -1.8 -15 -17.1* -20 Sema 2.4 mg Lira 3.0 mg Placebo 1 Observed data for the on-treatment period; *p-value <0.0001 vs lira 3.0 mg; % change in body weight measured as change from baseline Data shown is the trial product estimand; Sema: semaglutide; Lira: liraglutide
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