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Investor Presentaiton

Diabetes care Diabetes care sales in IO driven by both GLP-1 and insulin 9 Commercial execution and innovation DKK billion 60 60 50 40 40 30 20 20 10 10 Diabetes care sales and growth in IO 5% 6% 10% 11% 14% 0 2017 Insulin Novo NordiskⓇ Must-win battles for IO Drive insulin sales and patient base TRESIBA insulin degludec [rDNA origin] injection 37.7% NN basal value market share RYZODEG 70% insulin degludec and 30% insulin aspart [rDNA origin] injection 69.3% NN mix value market share Drive GLP-1 market growth OZEMPİC semaglutide injection RYBELSUS semaglutide tablets 27 launch markets 59.4% 2018 2019 2020 2021 Injectable GLP-1 Oral GLP-1 Other Diabetes care NN GLP-1 value market share Growth at CER IO: International Operations; CER: Constant exchange rates; NN: Novo Nordisk Source: Reported sales and growth at CER; IQVIA MAT value December 2021 CMD22 CAPITAL MARKETS DAY
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