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Investor Presentaiton

Novo Nordisk Annual Report 2023 Non-IFRS financial measures (part of the Management review - not audited) In the Annual Report, Novo Nordisk discloses certain financial measures of the Group's financial performance, financial position and cash flows that reflect adjustments to the most directly comparable measures calculated and presented in accordance with IFRS. These non-IFRS financial measures may not be defined and calculated by other companies in the same manner, and may therefore not be comparable. The non-IFRS financial measures presented in the Annual Report are: Net sales and operating profit in constant exchange rates (CER) ⚫ 'Net profit', adjusted for 'income taxes', 'financial items', 'depreciation and amortisation' and 'impairment losses' (EBITDA) Return on invested capital (ROIC) Free cash flow Cash to earnings Net sales IFRS Part of the Management review - not audited Net sales in constant exchange rates DKK million 2023 2022 232,261 Effect of exchange rate 7,658 Net sales in constant exchange rates Net sales previous year 239,919 176,954 % increase/(decrease) in reported currencies 31.3% 176,954 (13,024) 163,930 140,800 25.7% 2021 140,800 3,643 144,443 126,946 10.9% % increase/(decrease) in constant exchange rates Earnings before interest, taxes, depreciation, amortisation and impairment losses (EBITDA) EBITDA is defined as 'net profit', before 'income taxes', 'financial items', 'depreciation and amortisation' and 'impairment losses'. Management believes EBITDA is a useful measure as it helps analyse operating results from core business operations without including the effects of capital structure, tax rates, depreciation, amortisation and impairment losses. The following table shows a reconciliation of EBITDA with operating profit, the most directly comparable IFRS financial measures: 35.6% 16.4% 13.8% Operating profit in constant exchange rates EBITDA DKK million 2023 2022 Operating profit IFRS 102,574 74,809 Effect of exchange rate 4,898 (7,578) 2021 58,644 2,332 DKK million 2023 2022 2021 Net profit IFRS 83,683 55,525 47,757 Income taxes IFRS 20,991 13,537 11,323 Operating profit in constant exchange rates Operating profit previous year 107,472 67,231 60,976 Financial income IFRS (2,945) (239) (2,887) 74,809 58,644 54,126 Financial expenses IFRS 845 5,986 2,451 % increase/(decrease) in reported currencies 37.1% 27.6% 8.3% Operating profit (EBIT) IFRS 102,574 74,809 58,644 43.7% 14.6% 12.7% Depreciation and amortisations Impairment losses 7,289 6,553 5,311 2,124 809 714 EBITDA 111,987 82,171 64,669 IFRS refers to an IFRS financial measure. Sales and operating profit growth in constant exchange rates 'Growth in constant exchange rates' means that the effect of changes in exchange rates is excluded. It is defined as sales/operating profit for the period measured at the average exchange rates for the same period of the prior year, compared with net sales/operating profit for the same period of the prior year. Price adjustments within hyperinflation countries as defined in IAS 29 'Financial reporting in hyperinflation economies' are excluded from the calculation to avoid growth in constant exchange rates being artificially inflated. Growth in constant exchange rates is considered to be relevant information for investors in order to understand the underlying development in sales and operating profit by adjusting for the impact of currency fluctuations. % increase/(decrease) in constant exchange rates 83
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