Orthofix Investor Presentation Deck

Complementary & Compelling Strengths Next generation differentiated artificial cervical disc #1 prescribed bone growth stimulator(1) portfolio in the U.S. Market leading cellular allograft(2) and only Lyograft. tissue form Strong limb reconstruction & deformity correction portfolio Historically strong cash flow with positive EBITDA ORTHOFIX® Sea Spine 1) 2) 3) ORTHOFIX® Sea Spine iDATA Bone Growth Stimulator Market / Electrical Stimulation Device Market, U.S. 2018 SmartTRAK® 2021 US Cellular Allografts Market - Revenues/Shares SmartTRAKⓇ US Instrumented Fusion Market (2020-2026E CAGR) Unique 7D Flash Surgical Navigation System Rapid product innovation. driving market-share taking with 45+ product launches since 2018 Broadest advanced DBM portfolio backed by growing body of clinical evidence Rapidly accelerating commercial channel Double-digit revenue growth at >5x market spine growth (3) 4

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