Plasma Market Dynamics & COVID19 Impact

North America and Asia-Pacific produce enough plasma for their internal use, but other regions must import IG made from US plasma Origin of Plasma for Fractionation - 2020 1% 19% 0% North America * ■Europe Asia & Pacific ** 15% Latin America 65% Middle East & Africa 2020 IG Usage by Region Since Europe consumes 25% of the worldwide IG supply but collects only 15% of the global plasma for fractionation, there is an imbalance that requires Europe to import IG produced from US plasma. 25% 12 (MRB)

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