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Investor Presentaiton

88 Investor presentation Full year 2022 While Norditropin® is the market leader within GHD market, SogroyaⓇ represents an opportunity for patients A portfolio offering across markets Novo Nordisk leadership in competitive hGH market DKK billion Value MS% Sogroya® launches 20 50% 15 10 5 40% 30% 20% 10% 0 0% Jan 2019 Dec 2021 Segment Value Novo Nordisk Pfizer -Merck Kgaa hGH: Human growth hormone; SGA: Small for gestational age, ISS; Idiopathic short stature Source: IQVIA, MAT Dec 2021; US panels for GHT has been removed from IQVIA from Jan 2022 version Eli Lilly -Roche SOGROYA® somapacitan norditropin® (somatropin) injection • Once-weekly efficacious treatment on par with NorditropinⓇ Appears to have safe profile and no injection site reactions Simple and easy-to-use device Phase 3 trials toward broad range of indications (e.g. SGA, Turner, Noonan, ISS) to expand the market NorditropinⓇ strategy Apply a market-fit approach to support specific markets and patient groups Broad label across eight indications Novo NordiskⓇ
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