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Investor Presentaiton

Patient A: Severity of Negative Symptoms Associated with Psychosis at Baseline and across 11 Months. Prescriber ratings were performed to evaluate the presence and severity of two negative symptom domains, avolition/apathy and asociality/low social drive (COMPASS Clinician Rating Form) for Patient A at baseline and across 11 months of NAVIGATE Coordinated Specialty Care services. NOTE: Graph lines are superimposed when severity levels of symptoms are identical. COMPASS Clinician Rating Form (anchor points): 0=Not Present, 1=Very Mild, 2= Mild, 3-Moderate, 4-Moderately Severe, 5-Severe, 6=Extremely Severe. (Source: Nevada NAVIGATE Early Treatment Program for First Episode of Psychosis) Patient A: Negative Symptoms Associated with Psychosis, Year 1 Prescriber ratings: Presence and Severity 5.5 5 4.5 4 3.5 3 2.5 2 1.5 1 0.5 0 -0.5 Base-line 1 mo 2 mos 3 mos 4 mos mos 6 mos 7 mos 8 mos 9 mos 10 mos 11 mos (0) Avolition 5 3 3 2 2 0 3 2 1 0 1 0 -Asociality 4 2 4 3 2 1 2 2 1 0 1 0
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