BioNTech Investor Day Presentation Deck

mRNA technology Multi-platform engine We are exploring taRNA and saRNA in multiple infectious disease programs Disease type SARS-COV-2 Influenza A virus HIV Ebola virus Lassa virus Marburg virus CCHFV Nipahvirus MERS-CoV uRNA uRNA mRNA modality modRNA modRNA CCHFV, Crimean-Congo hemorrhagic fever orthonairovirus; MERS-CoV, Middle East Respiratory syndrome-related coronavirus; modRNA backbone-optimized nucleoside-modified RNA; saRNA, self-amplifying mRNA; taRNA, trans-amplifying mRNA; URNA; backbone optimized uridine RNA. Internal data. saRNA saRNA saRNA saRNA saRNA saRNA saRNA saRNA ta RNA ta RNA ta RNA D 1 1 ta RNA ta RNA ta RNA BIONTECH 33

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