Second Quarter 2023 Earnings

Second Quarter 2023 Key Financial Metrics (In millions, except percentage data) Reported Revenue Growth Revenue Growth1 GAAP Net Income Non-GAAP Net Income2 Excluding KUVANⓇ $595 $545 $56 $105 $534 $476 +12% +14% $28 +102% $77 +37% Q2 2022 Q2 2023 Q2 2022 1 Includes total revenues excluding revenues from KUVAN. 2 7 Q2 2023 Q2 2022 Q2 2023 Q2 2022 Q2 2023 Non-GAAP Income is defined by the Company as reported GAAP Net Income, excluding amortization expense, stock-based compensation expense, contingent consideration, and, in certain periods, certain other specified items. The Company also includes a Non-GAAP adjustment for the estimated income tax impact of reconciling items. Refer to Non-GAAP Information on slide 10 of this presentation for reconciliations to the comparable information reported under U.S. GAAP. BIOMARIN

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