Investor Presentaiton

Chlamydia biology requires sophisticated vaccine design Chlamydia trachomatis (CT) is a bacterium that lives inside human cells Targeted immune profile 0 ° EB (elementary body) Y Antibodies may contribute to protection sanofi IFNY CD4 T cells Anti- bodies RB (reticulate body) Inclusion IFN-y producing CD4+ T cells are the primary mediators of protection Antibodies and CD4 T cell responses Recognition of multiple chlamydia serovars (serotypes) Broad population coverage (HLA: Human Lymphocyte Antigen) 102 Vaccines Investor Event

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