Phesgo and Tecentriq Performance and Approvals

Expected 2023 currency impact CHF / USD Assumed avg. YTD 2023 0% -3% -4% -4% 0.95 0.95 0.94 0.92 0.93 0.92 0.92 0.92 Roche Assuming the 31 March 2023 exchange rates remain stable until end of 2023, 2023 impact¹ is expected to be (%p): Q1 HY Sep FY 0.92 0.92 0.93 0.91 0.91 0.91 0.91 0.91 0.91 0.91 0.91 0.91 YTD Monthly avg fx rates 2023 Fx rates 31 Mar 23 Average YTD 2023 - Average YTD 2022 Sales -4 -5 -5 -4 CHF / EUR Assumed avg. YTD 2023 Core operating -5 -4 -4% -4% -2% -1% profit 1.04 1.03 1.01 Core EPS -6 -5 1.00 0.99 0.99 0.99 0.99 1.00 0.99 0.99 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 Monthly avg fx rates 2023 Fx rates 31 Mar 2023 Average YTD 2023 Average YTD 2022 1 On group growth rates 47

View entire presentation