IPTACOPAN ASH UPDATE slide image

IPTACOPAN ASH UPDATE

Significant experience in non-malignant hematology and rare disease provides strong foundation for launch Track record of execution in rare hematology / oncology conditions → Promacta market leadership in SAA (ultra-rare) and ITP (rare) based on deep understanding of HCP insights and patient needs / motivations; also an oral option in originally infusion-driven market → Building on rare disease playbook from Vijoice and Afinitor TSC launches, including early and critical focus on patient engagement and advocacy Existing → ~2.5k hematologists / oncologists seeing PNH patients relationships with → PNH treaters Rare disease, but treated and managed not just by experts in large centers, but also community HCPs 28 IPTACOPAN ASH UPDATE | DECEMBER 13, 2022 → Strong existing customer relationships with majority of PNH treaters → Top medical experts engaged in either clinical studies or advisory capacity → Account profiling underway to identify individual success levers NOVARTIS | Reimagining Medicine
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