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Investor Presentation

102 Investor presentation First six months of 2022 Novo NordiskⓇ Potential first human dose with cell therapy in collaboration with Heartseed and others Utilise internal capabilities and disease understanding for stem cell development Internal capabilities Therapeutic areas Accelerate innovation through partnerships iPSC derived cardiomyocyte spheroids for direct injection into heart GMP-grade production capability my Academic collaborations Ethical stem cell practices IP positions on differentiation protocols Heartseed • Parkinson's disease First human dose expected first half of 2022 Chronic heart 2 first human dose projects expected in 2022 failure LUND UNIVERSITY Type 1 diabetes BioLamina REVOLUTIONIZING CELL CULTURE Dry age-related macular degeneration UCSF University of California San Francisco . • • • hESC derived dopaminergic progenitor neurons for placing into the brain Parkinson's disease First human dose expected first half of 2022 Novo Nordisk scientists embedded at UCSF lab Process development, manufacturing, QA/QC, facilities and operations at Fremont site GMP: Good manufacturing practice; IP: Intellectual property; iPSC: induced pluripotent stem cells; QA/QC: Combination of quality assurance with quality assurance and quality control; hESC: Human embryonic stem cell
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