Investor Presentation - First Six Months of 2021 slide image

Investor Presentation - First Six Months of 2021

22 Investor presentation First six months of 2021 Novo NordiskĀ® Novo Nordisk's opportunity is in the large unmet needs across all therapy areas in scope DIABETES ~463 million -6% OBESITY ~650 million -2% HAEMOPHILIA ~0.5 million -25% People with diabetes People in good control People with People medically obesity treated People with haemophilia People being treated OTHER SERIOUS CHRONIC DISEASES * Gro 80% of diagnosed NASH patients are obese and 35% have T2DM 70% of diabetes patients die from atherosclerotic CVD 40% of patients hospitalised for heart failure are diabetic ~50% of the total CKD population suffers from diabetic nephropathy NASH: Non-alcoholic steatohepatitis, T2DM: Type 2 diabetes mellitus, CVD: Cardiovascular disease, CKD: Chronic kidney disease. Note: All figures are global and good control defined as A1C that is less than 7% Source: International Diabetes Federation; Diabetes Atlas 9th Edition 2019, IQVIA MIDAS 2017, World Federation of Haemophilia - Annual survey 2018; Abera SF et al. Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015, 2017; Heart Disease and Stroke Statistics, American Heart Association, 2017; Williams CD et al. Prevalence of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis among a largely middle-aged population utilising ultrasound and liver biopsy, 2011; Addressing the global burden of chronic kidney disease through clinical and translational research, 2014
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