BioAtla Investor Presentation Deck
Phase 1 results with CAB-ROR2 (BA3021) support advancing into Phase 2
in multiple indications
ROR2+ Tumor Types
NSCLC
Melanoma
SCCHN
bicatla
Results
▪
Partial response in 2 / 3 patients who previously experienced failure on PD-1
and who received Phase 2 dose or higher
▪ Complete response in 1 / 1 patient who previously experienced failure on PD-1
Clearance of pulmonary metastases followed by normalization of adenopathy
Continued complete response off treatment for over 2 years
■
■ Partial response in 1 / 1 ROR2+ refractory to four prior lines of therapy
including cetuximab and PD-1 (pembrolizumab)
Promising safety and tolerability profile across multiple tumor types
No ROR2 ADC or small molecules in the clinic to date, suggesting CAB-ROR2-ADC is a first-in-class
therapy across multiple tumor types
BioAtla| Overview 48View entire presentation