PaTHway Phase 3 Trial Analysis
4
Chronic Hypoparathyroidism: Significant Patient Population
USA
Estimated Prevalence: ~200K in these 3 regions
~70k-112k
Europe
~86k-223k
Japan
~25k-32k
•
2013, Powers et. al.,
Prevalence and Incidence of
Hypoparathyroidism in the United
States Using a Large Claims
Database, JBMR
2011, Clarke et. al., Co-morbid
Medical Conditions Associated with
Prevalent Hypoparathyroidism: A
Population-Based Study
2013, Underbjerg et. al.,
Cardiovascular and Renal
Complications to Postsurgical
Hypoparathyroidism: A Danish
Nationwide Controlled Historic Follow-
up Study
2015, The Epidemiology of
Nonsurgical Hypoparathyroidism in
Denmark: A Nationwide Case Finding
Study
2016, Astor et. al., Epidemiology and
Health-Related Quality of Life in
Hypoparathyroidism in Norway
2017. Shishiba et. al., Prevalence of
postsurgical hypoparathyroidism in
Japan: Estimated from the data of
multiple institutes
1999. Nakamura et. al., Prevalence of
Idiopathic Hypoparathyroidism and
Pseudohypoparathyroidism in Japan
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