Half-Year 2022 Financial and Clinical Trials Update slide image

Half-Year 2022 Financial and Clinical Trials Update

Tecentriq overview: Adjuvant program to read out in 2022/23 CHFM Tecentriq Q2 update Roche Ph III (IMvoke010) in adjuvant SCCHN continues to final analysis • YoY CER growth • +13% Japan: Sales impacted by mandatory price cut 1,000 900 800 +31% +54% 700 600 500 +146% 400 300 200 100 0 Lung franchise (NSCLC, SCLC) • . EU: Approval in adjuvant PDL1+ NSCLC achieved; Growth driven by 1L SCLC US: Strong launch in adjuvant PDL 1+ NSCLC Gl franchise (HCC) US/EU/Japan: Growth driven by 1L HCC Outlook 2022 • Further growth due to first-to-market indications Q2 19 Q2 20 Q2 21 Q222 • ■US Europe International Japan ⚫ Ph III Tecentriq adjuvant studies in HCC and neoadjuvant NSCLC reading out • ⚫ Ph III tiragolumab + Tecentriq in 1L EC reading out CER-Constant Exchange Rates; SCCHN-squamous cell carcinoma of the head and neck; NSCLC=non small cell lung cancer; SCLC-small cell lung cancer; HCC-hepatocellular cancer; EC-esophageal cancer 23
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