J.P. Morgan Healthcare Conference Presentation slide image

J.P. Morgan Healthcare Conference Presentation

World leader in infectious diseases, £105bn market Transforming prevention and treatment of infectious diseases for billions of people 2023 progress and what's next Arexvy (RSV2, older adult) >£3bn PYS³ ⚫ First to receive approval • (US, EU, JP, UK) Regulatory decision on at risk 50-59 adults expected in 2024 Shingrix (shingles) >£4bn PYS³ ⚫ Partnership with Zhifei in China. . Life-cycle innovation work ongoing Influenza >£3bn PYS³ Multivalent mRNA vaccine candidate trials underway; phase II data H1 2024 Meningococcal disease £1-2bn PYS³ • MenABCWY US file submission expected in H1 2024 . Pneumococcal disease >₤4bn PYS³ 24v phase III start for adults and resumption of paediatric phase II trial in 2024 Bepirovirsen (Hepatitis B) >£2bn PYS³ • Exclusive license for JNJ-3989 to expand development B-WELL phase III data from 2025 Anti-infectives ~£2bn PYS3 . Preparing file submissions for gepotidacin ⚫ Phase III trial underway for tebipenem Herpes simplex virus Phase I/II data in 2024 GSK 1. Evaluate Pharma, May 2023 2. Respiratory syncytial virus 3. PYS: Non-risk adjusted peak year sales potential is subject to certain assumptions consistent with those for previous outlooks, ambitions and expectations 6
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