Half-Year 2022 Financial Performance

CORE EBITDA Margin Robust profitability in challenging macro environment CORE EBITDA Margin Evolution H1 2022 vs H1 2021 in % Growth projects less dilutive vs H1 2021 Inflation and higher spending levels post-COVID partially offset by productivity Dilutive impact of third-party sales to former Lonza Specialty Ingredients H1 2021 CORE EBITDA margin Growth project impact Productivity/ operational excellence¹ Business mix / one-offs Third party Sales to former Specialty Ingredients business H1 2022 CORE EBITDA margin 1Includes inflationary impact Lonza 33.3 (0.9) 33.1 1.9 (0.7) CORE definition: See appendix (0.5) 12

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