Unlocking Hope for Cancer Patients Using PDT
13
BROAD-SPECTRUM ANTI-MICROBIAL POTENTIAL
POSSIBILITY FOR SEVERAL ANTIMICROBIAL TREATMENTS – WITHOUT RESISTANCE
-
“Antimicrobial resistance (AMR) is one of the top 10 threats facing humanity"
Leading Institutions: Viroclinics conducted virus
tests & ACARE (University of Adelaide) conducted
bacteria and fungi tests
World Health Organisation'
SARS-COV-2: Omicron
Selected Photosoft™ Compounds vs. Remdesivir
Broad Spectrum Potential: In vitro tests showed
Photosoft™ to be effective against several types of
pathogens, including antibiotic-resistant superbugs
Need for New Treatment Options: Potential for
PhotosoftTM as a new treatment class for
polymicrobial infections and/or where pathogens
cannot develop drug resistance
Given the general mode of action of PDT... it is unlikely
for superbugs to develop resistance to the compounds
Prof Darren J. Trott, Director, Australian Centre for Antimicrobial Resistance Ecology
(ACARE), University of Adelaide
1 https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance
"
% Inhibition
100
80
PhotosoftTM compounds
60
40
20
Remdesivir
0
0
0.1
0.2 0.3 0.4 0.5 0.6 0.7 0.8
Concentration μM
0.9
1
им
30
25
20
15
10
5
Broad Spectrum Activity: Minimum Inhibition
Concentration (MIC50) of Selected Photosoft Compound
following exposure to light for 5 minutesView entire presentation