Novavax Global Commercial Operations and COVID-19 Vaccine Update

Antigenic cartography of pseudovirus neutralization responses for adolescents novavax BA1 Primary : 2 Doses BA.4/5 田 Booster 3 Doses PROTOTYPE DELTA BA.4/5 DELTA PROTOTYPE BA.1 PREVENT-19 PRE-fusion Protein Subunit Vaccine Efficacy Novavax Trial | COVID-19 Fold Difference: Prototype BA.4/5 = 28.8 Fold Difference: Prototype → BA.4/5 = 1.74 Note: each square represents a 2-fold difference in neutralizing responses © 2023 NOVAVAX. All rights reserved. 43

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