OmniAb SPAC Presentation Deck
ZIMBERELIMAB APPROVED
THE FIRST APPROVED OMNIRAT-DERIVED ANTIBODY
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gloria
• On August 30, 2021, zimberelimab (GLS-010), an OmniAb-derived fully human anti-PD-1 mAb,
was approved in China for the treatment of recurrent or refractory classical Hodgkin's lymphoma
Marks the first approval of an OmniAb-derived mAb
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BIOSCIENCES
In 2015, GloriaBio contracted with WuXi Biologics to discover and develop zimberelimab in China
using OmniRat
Zimberelimab entered clinic in March 2017, and NDA was submitted to China NMPA in February 2020
GloriaBio is also investigating zimberelimab in advanced solid tumors, and was granted
Breakthrough Therapy designation for the treatment of patients with recurrent/metastatic cervical
cancer in March 2021
Zimberelimab is being developed by Arcus Biosciences (in collaboration with Gilead) in North
America, Europe, Japan and certain other territories through a 2017 agreement
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