40th Annual J.P. Morgan Healthcare Conference Presentation

Setting New Standards in Biological Drug Production Cell Culture TRENDS Process and N-1 intensification single-use technologies REPLIGEN RESPONSE R REPLIGEN Upstream Clarification R OPER TRENDS Fewer steps, smaller footprint single-use solutions REPLIGEN RESPONSE REPLIGEN h Downstream A REPLIGEN Acce Purification TRENDS TRENDS Scalable, flexible, single-use Scalable, flexible, single-use manufacturing manufacturing Process monitoring REPLIGEN RESPONSE FEPA SEN Depa REPLIGEN OPUS 4.5 UF/DF REPLIGEN RESPONSE REPLIGEN +M Ch FlowVPX™ ORT REPLICEN 24- 11

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