Brepocitinib Overview & RVT-3101 Update slide image

Brepocitinib Overview & RVT-3101 Update

2022 Has Been an Incredible Year for Roivant ... Commercial Launch of VTAMA Became #1 most prescribed branded topical for psoriasis 8 weeks into launch Executed first major PBM/payer contract Japanese partner reported positive topline results in Phase 3 trial in AD Demonstrated favorable PK and safety in pediatric subjects with AD Pipeline Composition RVT-3101 and brepocitinib: ☐ Announced collaborations with Pfizer IMVT-1402: Unveiled next- generation anti-FcRn Batoclimab: Announced new indications Optimized pipeline and extended runway by discontinuing six programs n Clinical Progress Brepocitinib: Initiated Phase 3 trial in DM Brepocitinib: Completed enrollment in global Phase 2B trial in SLE Namilumab: Initiated Phase 2 trial in sarcoidosis RVT-2001: Expanded ongoing Phase 1/2 trial in lower-risk MDS Batoclimab: Initiated Phase 3 trials in MG and TED Additional Upside Established multiple partnerships in targeted protein degradation with aggregate milestone payments over $1B plus product royalties roivant ли LNP patent litigation progressed in Roivant's favor For investor audiences only 3
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