RSV Seasonal Vaccine Introduction and Growth Strategy slide image

RSV Seasonal Vaccine Introduction and Growth Strategy

Delivering our commitments for attractive medium-term growth On track with continued organic and business development progress 2021-2026 outlook Sales Metric >5% CAGR Adj. operating profit >10% CAGR Vaccines Specialty Medicines General Medicines High-single-digit % CAGR Double digit % CAGR Broadly stable >30% by 2026 Cash generated from Operations >£10bn by 2026 Adj. operating margin On track Pipeline Arexvy. US FDA and EMA approved RSV1 vaccine for older adults MenABCWY: preliminary pivotal phase III data presented at ESPID2 Shingrix. approved in Japan for at-risk adults *413 NgG vaccine candidate for Neisseria gonorrhoeae: US FDA fast-track designation Jemperli. 1L EC3 indication granted priority review by US FDA Business Development Completion of BELLUS Health, Inc. acquisition and exclusive licensing agreement with Scynexis, Inc. GSK All guidance, outlooks, ambitions and expectations should be read together with the guidance, assumptions and cautionary statement in the Q2 2023 earnings release and the 2022 Annual Report. All outlook and ambition statements are given on a constant currency basis and use 2021 forecast exchange rates as a base, assuming a continuation of Q1 2021 closing rates. CAGR is for the 5 years to 2026, using 2021 as the base year. Pipeline sales are risk-adjusted and include anticipated sales of new products and Life Cycle Innovation (LCI) launched from 2021 onwards. Note: COVID therapeutic and vaccine solutions are excluded from the above. 1. Respiratory syncytial virus 2. European Society For Paediatric Infectious Diseases 3. Endometrial cancer. 6
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