Investor Presentation Q1 2018

Investor Presentation First three months of 2018 The GLP-1 segment accounts for 12% of the global diabetes care market value Slide 60 Global GLP-1 market GLP-1 value in bDKK VictozaⓇ exenatide dulaglutide Ozempic® other Share of total diabetes care market market GLP-1 value and patient share of the total diabetes care market Share of total diabetes care GLP-1 value share of total diabetes GLP-1 patient share¹ of total diabetes 70 10% 20% 60 8% 15% CAGR value¹: 34.0% 15% 50 12% 6% 11% 40 10% 30 4% 7% 5% 20 5% 5% 5% 2% 3% 10 1% 0 0% 0% Feb 2013 Feb 2018 World North Reg America EU Reg Reg Reg Reg AAMEO J&K LATAM China 1 CAGR for 5-year period Source: IQVIA monthly MAT Feb, 2018 value figures (DKK) changing diabetes® Reg: Region; AAMEO: Africa, Asia, Middle-East and Oceania; J&K: Japan & Korea; LATAM: Latin America. 1 Patient share is indicative and based on data for US, UK, Germany and France only. Source: Value data; IQVIA monthly MAT Feb, 2018. Patient data; IQVIA Disease Analyser (DE, FR, UK), QuintilesIQVIA LRX (USA), Feb 2018

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