Investor Presentation

120 Investor presentation First six months of 2022 Insulin market size and volume share of growth and market share in Region China Region China Total Insulin market share and market size (DKK billion) Market growth A Market share Insulin volume: market share 80% 50% 50% 15 14.7% +1.9% Long- acting 26% 80% Fast- acting 2 Premix 81% 4 37% Human 3 6 Novo Nordisk Competitors 40% 60% 51% 16.7% +5.2% 30% 46% 40% 20% 16.0% -0.3% 20% 17.4% +1.6% 0% May 2019 -NN market share 6.3% -3.8% Source: IQVIA, May 2022, LHS graph - Value, RHS Graph - Volume, MAT; NN: Novo Nordisk; Region China covers Mainland China, Taiwan, and Hong Kong 10% 5% 5% 0% May 2022 NN share of growth Market growth (right axis) NN growth (right axis)

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