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Investor Presentaiton

Novo Nordisk Annual Report 2023 Net sales - Business segments and geographical areas Introducing Novo Nordisk Strategic Aspirations Risks Management Consolidated statements Additional information Total International Operations Total North America Operations Total Novo Nordisk net sales Total IO EMEA China Rest of World 2023 2022 2021 2023 2022 2021 2023 2022 2021 2023 2022 2021 2023 Total NAO 2022 US 2021 2023 2022 2021 2023 2022 2021 DKK million Diabetes and Obesity care segment: Rybelsus® 7,389 OzempicⓇ 26,378 VictozaⓇ 4,850 3,155 17,369 5,672 524 4,232 8,856 14,327 1,714 289 131 63 3,026 10,417 6,393 4,821 2,196 303 7,230 Total GLP-1 38,617 26,196 16,106 6,726 2,166 20,725 2,724 3,527 1,256 1,478 1,544 1,428 1,378 4,756 1,470 14,855 10,209 6,208 3,737 1,847 11,684 7,604 Long-acting insulin 11,339 11,403 11,074 7,103 7,157 6,729 1,649 1,636 2,080 2,587 2,610 2,265 235 11,361 8,144 4,314 11,060 8,011 4,243 18,750 11,299 2,160 69,340 42,381 24,849 63,010 38,750 23,168 95,718 59,750 1,655 3,814 6,650 8,328 3,613 6,406 8,031 8,664 12,322 4,050 84,515 57,175 37,491 77,683 53,167 35,442 123,132 83,371 3,566 5,338 6,990 2,931 4,685 6,412 14,905 16,741 4,838 33,705 15,054 53,597 18,064 ⚫of which TresibaⓇ 5,864 6,092 5,486 3,435 3,485 2,979 848 1,050 1,095 1,581 1,557 1,412 1,888 3,261 4,243 1,333 2,723 3,793 7,752 9,353 9,729 of which XultophyⓇ 2,887 2,400 2,135 1,831 1,716 1,693 409 45 3 647 639 439 332 409 522 325 399 512 3,219 2,809 2,657 of which Levemir® 2,588 2,911 3,453 1,837 1,956 2,057 392 541 982 359 414 414 1,346 1,668 2,225 1,273 1,563 2,107 3,934 4,579 5,678 Premix insulin 9,342 10,023 10,512 2,570 2,622 2,879 4,441 4,912 5,224 2,331 2,489 2,409 232 539 691 216 517 665 9,574 10,562 11,203 of which Ryzodeg 3,730 2,889 1,711 587 495 392 1,965 1,218 283 1,178 1,176 1,036 3,730 2,889 1,711 ⚫ of which NovoMix® 5,612 7,134 8,801 1,983 2,127 2,487 2,476 3,694 4,941 1,153 1,313 1,373 232 539 691 216 517 665 5,844 7,673 9,492 Fast-acting insulin 10,415 10,826 10,903 6,695 6,456 6,454 1,545 1,942 2,288 2,175 2,428 2,161 5,534 6,637 6,784 5,265 6,247 ⚫of which Fiasp 1,512 1,354 1,106 1,266 1,138 965 246 216 141 661 649 642 618 606 6,357 605 of which NovoRapidⓇ 8,903 9,472 9,797 5,429 5,318 5,489 1,545 1,942 2,288 1,929 2,212 2,020 4,873 5,988 6,142 4,647 Human insulin 6,134 6,508 7,453 1,919 1,983 2,152 1,213 1,812 2,692 3,002 2,713 2,609 1,460 1,678 1,599 1,406 Total insulin 37,230 38,760 39,942 18,287 Other Diabetes care 1,987 2,428 Total Diabetes care 77,834 67,384 2,644 58,692 661 18,218 717 18,214 713 39,673 33,790 29,136 15,948 8,848 10,302 892 1,181 15,220 12,284 1,432 15,563 10,095 10,240 434 530 10,792 325 14,192 797 22,213 18,374 WegovyⓇ 1,913 54 1,913 54 SaxendaⓇ 6,402 5,832 3,117 3,780 3,561 Total Obesity care 8,315 5,886 3,117 5,693 3,615 Diabetes and Obesity care total 86,149 73,270 61,809 45,366 37,405 1,809 1,809 30,945 146 146 133 133 61 61 16,094 15,353 15,624 2,476 2,476 24,689 2,138 2,138 20,512 9,444 9,818 499 267 13,993 95,632 72,164 54,505 87,768 66,881 29,430 6,134 1,386 29,430 6,134 1,247 3,887 4,844 3,897 3,306 4,368 1,247 33,317 10,978 5,283 32,736 10,502 15,240 128,949 83,142 59,788 120,504 77,383 16,064 950 660 806 2,003 5,641 5,752 13,776 15,460 1,605 1,515 7,594 8,186 13,054 14,949 48,022 52,952 2,312 51,197 173,466 1,386 31,343 3,526 10,289 10,676 4,912 41,632 16,864 56,109 215,098 156,412 15,949 17,463 2,173 17,687 1,748 3,225 139,548 6,188 15,939 9,052 56,006 3,594 113,197 1,386 7,014 8,400 121,597 Rare disease segment: Rare blood disorders 6,432 6,671 5,784 4,021 3,795 3,712 372 604 222 2,039 2,272 1,850 5,344 5,035 4,433 5,070 of which Haemophilia A 1,939 1,769 1,625 1,271 1,137 1,162 223 81 24 445 551 439 483 569 487 468 4,710 543 4,170 11,776 11,706 10,217 460 2,422 2,338 2,112 ⚫of which Haemophilia B 584 479 400 377 294 268 13 13 4 194 172 128 477 280 237 336 152 102 1,061 759 637 ⚫ of which NovoSeven® 3,789 4,335 3,673 2,285 2,311 2,225 136 510 194 1,368 1,514 1,254 4,169 3,973 3,548 4,065 3,811 3,461 7,958 8,308 7,221 Rare endocrine disorders 2,045 4,904 4,880 699 2,232 2,212 216 246 167 1,130 2,426 2,501 1,791 2,234 2,423 1,757 2,205 2,400 3,836 7,138 7,303 Other Rare disease Rare disease total 1,006 1,002 1,064 781 804 837 5 6 6 220 192 221 545 696 619 203 358 330 1,551 1,698 1,683 9,483 12,577 11,728 5,501 Total sales by geographical area 95,632 85,847 73,537 50,867 Total sales growth as reported 11.4% 16.7% 11.7% 15.0% 6,831 44,236 17.3% 6,761 37,706 16,687 9.9% 2.9% 593 856 16,209 1.2% 395 3,389 4,890 16,019 28,078 25,402 13.7% 10.5% 28.2% 4,572 7,680 19,812 136,629 13.5% 50.0% 7,965 91,107 35.4% 7,475 7,030 7,273 67,263 127,534 84,656 10.1% 50.6% 34.4% 6,900 17,163 20,542 63,009 232,261 176,954 140,800 9.0% 31.3% 25.7% 19,203 10.9% 57
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