Investor Presentaiton

16 15 11 C C 1μm 22 S S ms3000-mw2500-u-hb Ciliary Body Sclera 200μm Probe Cornea No spheres present Spheres transported prior to therapy into supraciliary space post therapy Video courtesy of Murray Johnstone, MD showing shrinkage of tissue during treatment Prelazer Probe Sclera Comea OCT CB Sclera Post Love SuprachoroidalSpace TM Micropulse Effects ты Histology Supraciliary space enhanced by shrinkage of treated tissue SCIENTIFIC RATIONALE Early work demonstrates that shrinking ciliary tissue may create a supraciliary space thereby increasing uveoscleral outflow. MECHANISM OF ACTION The presumed mechanism of action of MicroPulse TLT is dominated by heat-induced changes in ciliary body morphology resulting in increased uveoscleral outflow. IRIDEX

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