Strategic Transformation 2023
All Treated RUBY Patients are VOE-free Since Reni-cel Infusion
editas
MEDICINE
Patient 1
Patient 2
Patient 3
Patient 4
Patient 5
Patient 6
Patient 7
Patient 8
Patient 9
Patient 10
6
11
11
7
7
7
9
4
12
VOES Prior to Informed Consent
-25 -20 -15 -10 -5
Months Prior to Informed Consent
0* 0^
VOE-free After Reni-cel Infusion
5
Months of Post-Reni-cel Follow-up
10
Data cutoff November 22, 2023. Due to limited follow up period after dosing, Patient 11 was not included.
Left panel ends at informed consent date: *Day of informed consent. Right panel starts at infusion date: ^Day reni-cel was infused.
reni-cel, renizgamglogene autogedtem cel; VOE, vaso-occlusive event.
Hanna R et al. Poster presented at ASH 2023; San Diego, CA, USA, 9-12 December.
15
All 10 patients who reached the Month 1 visit have been VOE-free since reni-cel infusion
Ruby
Severe VOE
Non-severe VOE
9View entire presentation