Avantor Results Presentation Deck

1 Core Organic Growth & Adjusted EBITDA (Quarterly) USD in millions Total Avantor, Global GAAP consolidated net sales Core organic growth COVID Impact Organic growth M&A Impact FX Impact Reported net sales growth GAAP gross profit Adjustments for Ritter & Masterflex¹ Adjusted gross profit (non-GAAP) GAAP SG&A expense Amortization Acquisition/Integration-related expenses2,3 Purchase accounting adjustments4 Other stock-based compensation (expense) benefit Restructuring & severance charges5 Reserve for certain legal matters Impairment charges Adjusted SG&A expense (non-GAAP) Other reconciliation items Depreciation Loss on extinguishment of debt Net foreign currency loss (gain) from financing activities Receipt of disgorgement penalty? Total other adjustments Adjusted EBITDA (non-GAAP) Navantor™ 1Q22 $1,950 $ $130 (39) $91 117 (43) $165 $ 1Q22 690 $690 383 (92) (4) 4 1 (2) 22 22 % 7.3% -2.2% 5.1% 6.6% -2.5% 9.2% O $24 % 35.4% 0.0% 35.4% 0.0% $291 14.9% 19.6% -4.7% -0.2% 0.2% 0.1% -0.1% 0.0% 1.1% 0.1% 0.0% 0.0% 1.2% $423 21.7% $ $118 (75) $42 91 (81) $52 2Q22 $1,911 2Q22 $ 648 (14) $662 0 (1) 352 18.4% (68) (3) -3.5% -0.2% 0.0% 0.0% 22 6 % 6.4% -4.1% 2.3% 4.9% -4.4% 2.8% 1 $29 % 0.0% $281 14.7% $404 33.9% -0.7% 34.6% 0.0% 0.0% 1.1% 0.3% 0.0% 0.0% 1.5% 21.2% $ $141 (59) $82 47 (107) $22 $ 3Q22 $1,857 3Q22 651 375 (80) (6) 35.0% 0.0% $651 35.0% 2 (1) 21 3 (1) % 7.8% -3.3% 4.5% 2.5% -5.8% 1.2% $23 % -0.1% 0.0% 0.0% $289 15.6% $384 20.2% -4.3% -0.3% 0.0% 0.1% 1.1% 0.2% -0.1% 0.0% 1.2% 20.7% 4Q22 $1,795 $ % $52 2.7% (92) -4.8% ($40) -2.1% 14 0.7% (87) -4.5% ($113) -5.9% $ 4Q22 615 (1) $615 363 (79) (5) 0 $279 22 2 7 $31 $360 % 34.2% 0.0% 34.3% 20.2% -4.4% -0.3% 0.0% 0.0% 0.0% 0.0% 0.0% 15.6% 1.2% 0.1% 0.4% 0.0% 1.7% 20.0% 1Q23 $1,780 $ ($35) (93) ($128) 0 (42) ($170) $ 1Q23 625 $625 394 (78) (9) (0) (5) 23 % -1.8% -4.8% -6.6% 0.0% -2.1% -8.7% 2 (0) $25 % -0.3% 0.0% 0.0% $302 16.9% 35.1% 0.0% 35.1% 22.1% -4.4% -0.5% 0.0% 0.0% 1.3% 0.1% 0.0% 0.0% 1.4% $346 19.4% 2Q23 $1,744 $ ($124) (50) ($174) 0 8 % -6.5% -2.6% -9.1% 0.0% 0.4% ($167) -8.7% $ 2Q23 590 33.8% 0.0% 33.8% $590 $518 (79) 1 0 (7) (1) 24 2 (2) % $24 (161) -9.2% $271 15.5% $343 29.7% -4.5% 0.0% 0.0% 0.0% -0.4% -0.1% 1.4% 0.1% -0.1% 0.0% 1.4% 19.7% 4

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