ATAI Investor Day Presentation Deck
Cognitive testing: subset of tasks from MCCB
MATRICS Consensus Cognitive Battery (MCCB): 10 tests measuring seven cognitive performance domains
speed of processing, attention/vigilance, working memory, verbal learning, visual learning, reasoning and problem solving, and social cognition
Hopkins Verbal Learning Test-Revised (HVLT-R) - Positive in multiple previous studies
Cognitive domain: verbal learning and memory
Procedure: learn and recall a list of 12 words-given 3 trials, then 20-25 minutes later
Outcome measurement: number of words recalled (immediate)
Brief Assessment of Cognition in Schizophrenia (BACS): symbol coding test
Cognitive domain: processing speed, attention & working memory
Procedure: matching symbols and numbers (1-9) as quickly as possible
Outcome measurement: number of correct responses
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Category fluency task
Cognitive Domain: processing speed (verbal ability and executive control)
Procedure: say as many words in 1 minute in a specific category (e.g. "animals")
Outcome measurement: number of appropriate items provided in the category
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