41st Annual J.P. Morgan Healthcare Conference slide image

41st Annual J.P. Morgan Healthcare Conference

mAbs, Gene Therapy and mRNA fueling our growth Monoclonal Antibodies Cell & Gene Therapy R REPLIGEN ~$150B Market 2021 Growing at >10% annually >$5B Market 2021 Growing at >25% annually >140 U.S. FDA Approvals incl. 26 Biosimilars 14 U.S. FDA Approvals incl. 9 Cell, 5 GT >800 Phase I-III >1,500 Active clinical trials >500 Phase I-III >1,100 Active clinical trials New approvals and growing biosimilars pipeline Emerging opportunities beyond COVID Data sources: $s Company filings/guidance; Approvals: U.S. FDA website; Industry articles incl. www.genengnews.com/a-lists/top-11-best-selling-covid-19-vaccines-and-drugs-of-h1-2021/mAb approvals: Antibody therapeutics approved or in regulatory review in the EU or US - The Antibody Society/; PHrMA report https://phrma.org/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/PDF/A-C/MID-cell-and- gene-therapy-2020.pdf; Repligen internal mAbs tracker; Market research reports (Research and Markets, Allied Market Research, Brandessence Research, Fortune Business Highlights, Qualiket Research.. Candidates C&GT: 2)Cell & Gene Therapy reports: American Society of Gene + Cell Therapy: Q2 2022 Cell, Gene & RNA Therapy Trials C&GT: BioCentury 8
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