Evotec Investor Day Presentation Deck

evotec PAGE 34 سمجھے - 15 million RCC patients in US and EU High unmet medical need, no effective treatment P2X3 antagonist - Eliapixant (BAY1817080) Refractory Chronic Cough (RCC) ● Disease • RCC persists > 8 weeks; present despite guideline-based treatment Symptoms include dry irritable sensation in the throat. Symptoms not limited to coughing, may include globus, dyspnea, and dysphonia¹) • Cough refractory to treatment and/or unexplained Standard of Care • No effective treatment approved BAYER ¹) Song WJ, Chang YS, Faruqi S, et al. (2016). Defining Chronic Cough: A Systematic Review of the Epidemiological Literature. Allergy Asthma Immunol Res. 2016 Mar. 8 (2):146-55. BAYER

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