Connecting Innovation to Purpose slide image

Connecting Innovation to Purpose

Padcev® projected to reach up to ~$5B in global sales by 2028 6 L PADCEV. enfortumab vedotin-ejfv Injection for IV infusion 20 mg & 30 mg vials Latest Padcev® 03 revenues ¹ 1 (dollars in millions) Total Net Product Sales ADCETRIS PADCEV TUKYSA TIVDAK Ⓡ Three months ended September 30, 2022 2023 % Change $ 571 $ 428 33 $ 246 $ 219 13 $ 200 $ 105 89 $ 102 $ 88 $ 23 $ 16 16 40 % % % % % Nine months ended September 30, % Change 27 25 2023 $ 1,583 $ 751 $ 479 $ 289 $ 64 2022 $ 1,243 $ 601 $ 329 $ 267 $ 45 46 Sources: 1. SGEN Q3 earnings report, 2. SGEN press release, October 2023, 3. Evaluate Pharma 8 42 % % % % % 22nd October 2023 ² Groundbreaking EV-302 Trial Significantly Extends Overall Survival and Progression-Free Survival in Patients Treated with PADCEV® (enfortumab vedotin-ejfv) and KEYTRUDAⓇ (pembrolizumab) in First-Line Advanced Bladder Cancer 2021 PADCEVⓇ Global Projected Revenues in UC/Bladder³ $5B 2022 2023 2024 2025 2026 2027 2028
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