J.P. Morgan Healthcare Conference

FORWARD-LOOKING STATEMENTS BioCryst's presentation contains forward-looking statements, including statements regarding future results, preliminary, unaudited net revenue results, and forward-looking financial information and company performance or achievements. These statements are subject to known and unknown risks, uncertainties and other factors which may cause our actual results, performance or achievements to be materially different from any preliminary, unaudited net revenue results and future results, performance, or achievements expressed or implied in this presentation. These statements reflect our current views with respect to future events and are based on assumptions and are subject to risks and uncertainties. You should not place undue reliance on the forward-looking statements. For additional information, including important risk factors, please refer to BioCryst's documents filed with the SEC and located at ir.biocryst.com/financial-information/sec-filings bio cryst | 2

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