Evotec Investor Day Presentation Deck

evotec PanOmics Data generation • Patient-derived in vitro disease model • High-throughput screen • Transcriptome analysis in 384 well format PAGE 62 Unbiased identification of disease relevant drug candidates Screening to revert molecular patient profiles to the healthy state Transcriptome profiles induced by individual compounds in patient-derived cellular disease model UMAP Component 2 3- 2 1 -2- -3- Diseased -5 -1 0 UMAP Component 1 Healthy Unwanted / toxic effects 2 PanHunter Data analytics Identifies most suitable chemical hits • Focus on reversal of molecular disease phenotype • Weed out unwanted mechanisms

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