Avantor Results Presentation Deck

3 Regional Core Organic Growth & Adjusted EBITDA (Quarterly) (Dollars in millions) Americas GAAP consolidated net sales Core organic growth COVID Impact Organic growth M&A Impact FX Impact Reported net sales growth Adjusted EBITDA (non-GAAP) Adjusted EBITDA margin Adjusted EBITDA margin growth (-bps) Europe GAAP consolidated net sales Core organic growth COVID Impact Organic growth M&A Impact FX Impact Reported net sales growth Adjusted EBITDA (non-GAAP) Adjusted EBITDA margin Adjusted EBITDA margin growth (-bps) AMEA GAAP consolidated net sales Core organic growth COVID Impact Organic growth M&A Impact FX Impact Reported net sales growth Adjusted EBITDA (non-GAAP) Adjusted EBITDA margin Adjusted EBITDA margin growth (-bps) Navantor™ $ $57 74 $131 O 5 $136 $ $13 42 $55 0 51 $106 1Q21 $1,035 $252 24.3% 320 bps % 6.3% 8.3% 14.6% 0.0% 0.5% 15.1% $ $21 0 $21 0 4 $24 1Q21 $650 % 2.4% 7.7% 10.1% 0.0% 9.4% 19.5% $131 20.2% 330 bps 1Q21 $100 % 27.1% 0.1% 27.2% 0.0% 4.8% 32.0% $23 22.6% 490 bps $ $157 45 $203 0 10 $212 $ $88 (2) $86 0 59 $145 $ $29 (12) $16 0 2Q21 $1,070 6 $23 % 18.3% 5.3% 23.6% 0.0% 1.2% 24.8% $252 23.5% 50 bps 2Q21 $666 % 16.9% -0.4% 16.5% 0.0% 11.3% 27.8% $124 18.6% 170 bps 2Q21 $123 % 28.7% -12.3% 16.4% 0.0% 6.2% 22.6% $29 23.2% 70 bps $ $58 28 $87 4 4 $95 3Q21 $1,045 % 6.1% 3.0% 9.1% 0.5% 0.4% 10.0% $ $17 (2) $15 5 2 $22 $236 22.6% 120 bps 3Q21 $675 $ % $60 10.6% 2 0.3% $62 10.9% 7.5% 42 9 $113 1.6% 20.0% $136 20.1% 260 bps 3Q21 $115 % 18.5% -2.1% 16.4% 5.1% 2.6% 24.1% $30 25.7% 300 bps $ $58 (27) $31 31 1 $63 $ $15 (12) $3 43 (20) $27 $ $9 1 $10 18 (1) $27 4Q21 $1,088 % 5.7% -2.6% 3.0% 3.0% 0.1% 6.2% $238 21.9% 130 bps 4Q21 $686 % 2.3% -1.9% 0.5% 6.6% -3.0% 4.0% $148 21.6% 350 bps 4Q21 $134 % 8.2% 1.1% 9.3% 17.2% -1.2% 25.3% $33 24.9% 350 bps $ $81 (19) $62 47 (1) $108 $ $41 (24) $17 52 (40) $30 $294 25.7% 140 bps $ $9 3 $12 18 1Q22 $1,143 (3) $27 % 7.8% -1.8% 6.0% 4.6% -0.1% 10.5% 1Q22 $680 % 6.3% -3.7% 2.6% 8.1% -6.1% 4.6% $143 21.1% 90 bps 1Q22 $127 % 8.6% 3.1% 11.7% 17.7% -2.8% 26.6% $29 23.1% 50 bps $ $87 (42) $45 45 (4) $87 2Q22 $1,157 $290 25.1% 160 bps $ $31 (33) ($2) 31 (71) ($42) $ ($0) (1) ($2) 15 (6) $7 % 8.1% -3.8% 4.3% 4.2% -0.4% 8.1% 2Q22 $624 % 4.7% -4.9% -0.2% 4.6% -10.7% -6.3% $119 19.1% 50 bps 2Q22 $130 Note: the sum of Americas, Europe, and AMEA does not equal Total, Avantor. Does not include corporate-level expenses % -0.3% -1.0% -1.3% 11.8% -4.6% 5.9% $36 27.7% 450 bps $ $92 (40) $52 31 (4) $78 3Q22 $1,123 $ $17 7 $24 9 (9) $24 % 8.8% -3.9% 4.9% 2.9% -0.3% 7.5% $262 23.4% 80 bps $ $32 (26) $7 7 (93) ($80) 3Q22 $595 % 4.8% -3.8% 1.0% 1.1% -13.9% -11.8% $130 21.9% 180 bps 3Q22 $138 % 15.1% 5.7% 20.8% 7.8% -8.0% 20.6% $36 25.8% 10 bps $ $1 (45) ($44) 10 (5) ($39) 4Q22 $1,048 $ $8 (5) $3 2 $ $43 (42) $1 2 (72) ($69) (9) ($4) % 0.1% -4.1% -4.1% 0.9% -0.5% -3.6% $231 22.0% 10 bps 4Q22 $617 % 6.3% -6.1% 0.2% 0.3% -10.5% -10.1% $131 21.2% -40 bps 4Q22 $130 % 5.7% -3.5% 2.2% 1.5% -6.7% -3.1% $40 31.1% 620 bps 6

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