Avantor Results Presentation Deck

2 Core Organic Growth & Adjusted EBITDA (Annual) (Dollars in millions) Navantor™ Total Avantor, Global GAAP consolidated net sales Core organic growth COVID Impact Organic growth M&A Impact FX Impact Reported net sales growth GAAP gross profit Adjustments for Ritter & Masterflex¹ Adjusted gross profit (non-GAAP) GAAP SG&A expense Amortization Acquisition/Integration-related expenses2,3 Purchase accounting adjustments* Other stock-based compensation (expense) benefit Restructuring & Severance Charges5 Adjusted SG&A expense (non-GAAP) Other reconciliation items Depreciation Loss on Extinguishment of Debt Net foreign currency loss (gain) from financing activities Receipt of disgorgement penalty Total other adjustments Adjusted EBITDA (non-GAAP) FY2020 $6,394 $ $71 $266 $337 $0 $17 $353 FY2020 $ 2,080 (1) (12) $1,036 88 347 $2,080 $1,374 21.5% (307) (17) -4.8% -0.3% 0.0% 0.0% -0.2% 16.2% (1) % 1.2% 4.4% 5.6% 0.0% 0.2% 5.8% $434 $1,142 % 32.5% 0.0% 32.5% 1.4% 5.4% 0.0% 0.0% 6.8% 17.9% FY2021 $7,386 $ $582 138 $719 143 130 $993 FY2021 % 9.1% 2.2% 11.3% 2.2% 2.0% 15.5% $ 2,503 33.9% (6) -0.1% $2,509 33.9% 88 12 1 (13) $89 1,531 20.7% (291) -3.9% (94) -1.3% 0.0% (3) 0.0% (5) -0.1% $1,138 15.4% $1,459 % 1.2% 0.2% 0.0% -0.2% 1.2% 19.7% FY2022 $7,512 $ $441 (266) $175 268 (317) $126 FY2022 $ 2,603 34.6% (14) -0.2% $2,617 34.8% 1,473 (318) (19) 4 3 (4) $1,140 87 13 7 % 6.0% -3.6% 2.4% 3.6% -4.3% 1.7% $107 $1,571 % 19.6% -4.2% -0.2% 0.1% 0.0% 0.0% 15.2% 1.2% 0.2% 0.1% 0.0% 1.4% 20.9% 5

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