BioNTech Investor Day Presentation Deck

Identification of the patient's cancer mutations 2 3 Individual patient samples (blood and tissue) Normal 1 Cancer NORMAL GGGAAACTTTTTCC TUMOR GGGAAACGTTTTCC Mapping of mutations Sequencer Neoantigen prediction DNA DNA RNA On-demand tailored RNA manufacturing TAU 4 Mutation 5 H& Individualized immunotherapy Target discovery Cancer mutanome BIONTECH 22

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