Matinas BioPharma Investor Presentation Deck
8
MAT2203: Unlocking the Full Potential of Amphotericin B
Innate Amphotericin B
Characteristics
POTENT -
broad-spectrum fungicidal
ā Minimal drug-drug interactions
Low propensity for resistance
Active against susceptible and
emerging drug-resistant fungal
infections
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X
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IV Amphotericin B
Limitations
Only available through
IV administration
Significant toxicity and
side effects
High systemic exposure
distributed throughout the body
Must be administered in
hospital, increasing costs
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Unlocked
Potential
2024
Available systemically
and orally (crosses BBB following
oral administration)
Well-tolerated and safe
Delivered directly into infected
tissues
MAT2203 is a promising potential therapeutic option
for the treatment of MULTIPLE serious and life-threatening fungal infections
Cost-effective with potential for
ā significant health economic
benefits
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